TRICHOSTATIN A STABILIZES THE EXPRESSION OF PLURIPOTENT GENES IN HUMAN MESENCHYMAL STEM CELLS DURING EX VIVO EXPANSION.

Trichostatin A stabilizes the expression of pluripotent genes in human mesenchymal stem cells during ex vivo expansion.

BACKGROUND: Mesenchymal stem cells (MSCs) have been considered as ideal cells for the treatment of a variety of diseases.However, aging and spontaneous differentiation of MSCs during culture expansion dampen their effectiveness.Previous studies suggest that ex vivo aging of MSCs is largely caused by epigenetic changes particularly a decline of hist

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Genetics and caries: prospects

Caries remains the most prevalent non-contagious infectious disease in humans.It quick sling heater mount is clear that the current approaches to decrease the prevalence of caries in human populations, including water fluoridation and school-based programs, are not enough to protect everyone.The scientific community has suggested the need for innov

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